Ambersentan is a new drug being developed for treatment of pulmonary
hypertension. I would like information about the drug and also who is
developing it. |
Request for Question Clarification by
synarchy-ga
on
20 Sep 2002 10:20 PDT
I'm not having any luck turning up any information about a drug with
that name - what is the context in which you heard of it (ie is it
from Hong Kong, Europe, or parts other than the US, or any other
information you might have)?
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Clarification of Question by
lynnzs-ga
on
20 Sep 2002 10:46 PDT
The drug is in early stage of development in the United States, soon
to go into clinical trials, I believe. It is in the class of drugs
called Endothelin Receptor Antagonists. An FDA approved drug of this
class is Tracleer, produced by Actelion. Another of this class still
in clinical trials is Sitaxsentan, produced by Texas Biotech/Icos.
Ambersentan is supposedly the next generation after Sitaxsentan. I
learned of it after hearing about it at a Pulmonary Hypertension
conference in June.
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Request for Question Clarification by
voila-ga
on
20 Sep 2002 10:58 PDT
There's also epoprostenol sodium (Flolan) and Remodulin and I'm also
checking on fossilized amber but maybe synarchy-ga can help you with
this first.
http://www.uihealthcare.com/news/pacemaker/2002/summer/janetyoung.html
http://www.mosbysdrugconsult.com/DrugConsult/newapp2002.html
Cheers,
V
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Request for Question Clarification by
voila-ga
on
20 Sep 2002 11:31 PDT
Also "enrasentan" from GlaxoSmithKline and something called "U-15" in
clinical trials. Do you know if this is an oral med? inhaled? subq?
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Request for Question Clarification by
voila-ga
on
20 Sep 2002 12:31 PDT
Phew, finally found it; it's "ambrisentan" manufactured by Myogen
Products and is also used as an inhibiting factor for stent-induced
restenosis and for chronic renal disease. If you need additional
references as this drug relates to pulmonary hypertension, I will be
glad to locate them for you this weekend, if you will allow me.
Otherwise, another researcher should be able to pick up the clues and
give you the full scenario. Please let us know your wishes and thanks
very much for using Google Answers.
http://www.myogen.com/pages/Products.html
Search criteria:
endothelin receptor antagonist+next generation
endothelin receptor antagonist+2002
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Clarification of Question by
lynnzs-ga
on
20 Sep 2002 13:09 PDT
Thank you so much! Yes, that is it--sorry about the misspelling. And
you successfully found Flolan and Remodulin (UT-15), two of three
available treatments for pulmonary hypertension! Good job! This is
my first query to Google Answers, so I'm not sure if I am supposed to
close the query or what happens next, but I have enough information
for now.
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