Hi! Thanks for your very important question. I will list here some of
the research and articles mentioning researches and studies for ADHD
in 2002. I will provide some quotations from the articles so as to
save you time but I highly suggest that you read the whole document.
“Doctors at 12 hospitals and medical centers around North America
studied 136 children ages 7-14 who had both ADHD and tics. Children
received either MPH, clonidine, both, or neither; doctors, nurses,
parents, teachers and children did not know which children received
which treatment until the study was completed. Children were examined
by nurses and doctors, and their behavior was monitored and reported
by parents and teachers for 16 weeks.”
“Kurlan says doctors had assumed MPH shouldn't be used in children
with Tourette's because it was thought that the medicine, a stimulant,
would worsen tics. But the study found otherwise: Not only did
youngsters treated with MPH experience no more tics than their
counterparts not on MPH, dispelling that long-held notion, but the
medicine actually eased their tics. The same was true for children in
the other two groups that received medication.”
New Treatment Options for Children with ADHD
http://www.urmc.rochester.edu/pr/News/adhd.htm
“For decades, doctors who have treated children with both attention
deficit-hyperactivity disorder (ADHD) and tics have been warned not to
prescribe methylphenidate (Ritalin), the most common drug for ADHD,
because of a concern that it would make the tics worse. Now, the first
randomized, placebo-controlled clinical trial of methylphenidate and
another drug, clonidine (Catapres), has found that in fact these drugs
do not adversely affect tics. The researchers also found that a
combination of the drugs is more effective than either drug alone.”
Methylphenidate and Clonidine Help Children With ADHD and Tics
Tuesday, April 02, 2002
http://accessible.ninds.nih.gov/news_and_events/news_article_adhd.htm?type=current
“The NIEHS scientists and colleagues at the University of North
Carolina School of Medicine in Chapel Hill reported that when they
queried parents in a "typical" county of rural and suburban homes —
Johnston County, N.C. — the parents reported more than 15 percent of
boys in grades one through five had been diagnosed with ADHD and about
10 percent (or two-thirds of those diagnosed) were taking medication
for the condition. Asking the parents was a key to the higher figures,
the researchers thought, because school nurses might not be aware of
children who are receiving medication treatment entirely at home."
“Impact of Attention Deficit-Hyperactivity May Be Underestimated”
http://www.nih.gov/news/pr/feb2002/niehs-04.htm
“The majority of young boys with attention-deficit/hyperactivity
disorder (ADHD) are no more likely to exhibit destructive, delinquent
behavior as teenagers than children without the disorder, researchers
report.”
“Most Adhd Boys at No Higher Risk for Delinquency”
http://www.nlm.nih.gov/medlineplus/news/fullstory_9118.html
“'The results suggest we can identify brain mechanisms that may not be
fully functional in ADHD patients,’ Pliszka says. 'This study will
allow us to confirm or refute one of the major theories of ADHD --
that functioning of a particular area of the frontal lobe is altered.
It will lead to a better understanding of the causes of ADHD and, in
conjunction with other research, we might be able to develop new
treatments.'”
NIH funds local study on attention deficit disorder
http://www.bizjournals.com/sanantonio/stories/2002/07/29/daily32.html
The following articles are from the MEDLINE website and would require
a separate fee to read the whole article but it publishes an easy to
understand abstract including findings which would be beneficial to
your research.
“Five hundred eighty-four children were randomized, 563 were included
in the intent-to-treat population, and 509 completed the entire study.
Intention-to-treat analysis of Conners Global Index Scale for Teachers
and Conners Global Index Scale for Parents scores revealed significant
improvement in morning, afternoon, and late afternoon behavior for all
active treatment groups versus placebo. All active treatment groups
showed significant dose-related improvement in behavior from
baseline.”
“A randomized, double-blind, placebo-controlled, parallel-group study
of SLI381 (Adderall XR) in children with
attention-deficit/hyperactivity disorder.” By Biederman J, Lopez FA,
Boellner SW, Chandler MC.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12165576&dopt=Abstract
“This study comprehensively evaluated driving in adults with ADHD by
comparing 105 young adults with the disorder (age 17-28) to 64
community control (CC) adults on five domains of driving ability and a
battery of executive function tasks. The ADHD group self-reported
significantly more traffic citations, particularly for speeding,
vehicular crashes, and license suspensions than the CC group, with
most of these differences corroborated in the official DMV records.
Cognitively, the ADHD group was less attentive and made more errors
during a visual reaction task under rule-reversed conditions than the
CC group.”
“Driving in young adults with attention deficit hyperactivity
disorder: knowledge, performance, adverse outcomes, and the role of
executive functioning.” By Barkley RA, Murphy KR, Dupaul GI, Bush T.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12164675&dopt=Abstract
“The authors used functional magnetic resonance imaging (fMRI) to test
the effects of methylphenidate on steady-state blood volume in the
midline vermis of the cerebellum in boys with attention deficit
hyperactivity disorder (ADHD).”
“Moderate and high doses of methylphenidate increased T(2) relaxation
time in a rate-dependent manner-increasing T(2) relaxation time in the
most active children with ADHD and reducing T(2) relaxation time in
subjects with ADHD who were not objectively hyperactive.”
“Effects of methylphenidate on functional magnetic resonance
relaxometry of the cerebellar vermis in boys with ADHD.” By Anderson
CM, Polcari A, Lowen SB, Renshaw PF, Teicher MH
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12153824&dopt=Abstract
“To assess the comparability of atomoxetine, a new therapy for
attention deficit/hyperactivity disorder (ADHD) and methylphenidate.
(Atomoxetine was originally called tomoxetine. The name was recently
changed in order to avoid any potential confusion with tamoxifen that
might lead to errors in dispensing drug.) METHOD: Children with ADHD
were randomized to open-label atomoxetine or methylphenidate for 10
weeks.”
“Atomoxetine and methylphenidate treatment in children with ADHD: a
prospective, randomized, open-label trial.”
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12108801&dopt=Abstract
These are just a few of the MEDLINE abstracts and could give you a
clue on what other information maybe present in the site. There are
more 2002 abstracts that could be found from the MEDLINE site for ADHD
research.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&term=Attention+Deficit+Disorder+With+Hyperactivity[majr]+AND+english[la]+AND+human[mh]+AND+(review[ptyp]+OR+review+literature[mh]+OR+practice+guideline[ptyp]+OR+guideline[ptyp]+OR+clinical+trials[mh]+OR+clinical+trial[pt]+OR+consumerj[sb])&db=PubMed&orig_db=PubMed&filters=on&pmfilter_EDatLimit=210+Days&tool=MedlinePlus
Search terms used:
2002 ”new research” “Attention Deficit HyperActivity Disorder"
I hope these links would help you in your research. Before rating this
answer, please ask for a clarification if you have a question or if
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Regards,
Easterangel-ga |
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