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Q: New Antibiotics ( Answered 4 out of 5 stars,   0 Comments )
Question  
Subject: New Antibiotics
Category: Health
Asked by: rosemary25-ga
List Price: $18.00
Posted: 23 Sep 2002 10:29 PDT
Expires: 23 Oct 2002 10:29 PDT
Question ID: 68105
Where do you find information on ongoing clinical trials (both animal
and human) for new antibiotics?
Answer  
Subject: Re: New Antibiotics
Answered By: clouseau-ga on 23 Sep 2002 11:35 PDT
Rated:4 out of 5 stars
 
Hello rosemary25,

And thank you for your question.

I searched for antibitoic clinical tests and found many hits, over
60,000 as a matter of fact, but mainly individual university or clinic
listings rather than a compilation.

One good site, however is the NIH - National Institute of Health
Clinical Alerts and Advisories at
http://www.nlm.nih.gov/databases/alerts/clinical_alerts.html .

An example of the the individual listing I found include Children's
Hospital of the King's Daughters at
http://www.chkd.org/about_us/cpr_clinicaltrialsunit_currenttrials.asp
which lists Research Programs at the CPR  / Current Clinical Trials -
September 2002 complete with contact information for each program.
There are many like this in my search results and a search like this
might be helpful for you.

I continued to look for a broader listing source. I tried refining my
search to "new antibiotic" clinical trials listing and reduced the
hits to 90, but again produced listings by clinic, university or
hospital and in some cases modality, such as dermatology.

I went over to the FDA home page at www.fda.gov and searched for
listings of clinical trials directory. I began to find better lists.

http://www.clinicaltrials.gov/ is a searchable government database of
clinical trials and is described as:

"ClinicalTrials.Gov  This source provides patients, families and
members of the public easy access to information about the location of
clinical trials, their design and purpose, criteria for participation,
and, in many cases, further information about the disease and
treatment under study."

I searched antibiotic and found 43 studies. This will probably be one
of the best "single source" directories for your quest for trial
information. The database can also be queried very specifically as
shown here:

Search by Specific Information

Focused Search - search by disease, location, treatment, sponsor...

Browse

Browse by Condition - studies listed by disease or condition
Browse by Sponsor - studies listed by funding organization

Resource Information

Understanding Clinical Trials - information explaining and describing
clinical trials
What's New - studies in the news
MEDLINEplus - authoritative consumer health information
NIH Health Information - research supported by the National Institutes
of Health

I then searched clinical trials directory at Google and found
http://www.centerwatch.com/professional/cwpipeline/ - CenterWatch,
Clinical Trials Listing Service. They describe the site as:

"CenterWatch Drugs in Clinical Trials Database
Thank you for visiting the new online Directory of Drugs in Clinical
Trials! CenterWatch has recently improved this online service.
Enhancements include more effective and user-friendly search tools, a
larger number of drugs and more descriptive drug profiles.

The Directory of Drugs is a comprehensive online resource offering
detailed profiles of new investigational treatments in phase I through
III clinical trials. Updated weekly, the online directory provides
information on more than 1,800 drugs for more than 600 disease
conditions worldwide in a well-organized and easy-to-reference format.
Detailed profile information is provided for each drug."

This is a subscription site, however and costs are:

A 12 month subscription to this service is $295 for CenterWatch
Monthly Newsletter subscribers and $389 for non subscribers. If you
are unsure if you subscribe to the monthly newsletter, please call our
customer service center at 800-765-9647 for more information.

A European site I came across is http://clinicaltrialfinder.com/
Clinical Trial Finder. Thsi site also requires registration and
appears to be free, however states:

"This website is restricted to the medical profession, their immediate
colleagues,  those associated with clinical research and healthcare
industry professionals"

If you qualify, you might register here.

The Clinical Research Investigator RegistryTM at
http://www.criregistry.com/ describes itself as:

"...contains vital information about physicians, clinics, Clinical
Research Organizations and Trial Managment Organizations who conduct
clinical research trials for Pharmaceutical, Biotechnical and Medical
Device companies.  You may use this registry without charge to locate
and contact those conducting clinical research studies.  Physicians,
clinics, Clinical Research Organizations and Trial Management
Organizations have provided the following information:

Introduction/Summary of site's mission or purpose
 
Locations, facilities and affiliations 

Therapeutic areas, specialties and patient demographics 

Listings of faculty and staff..."

This may hold information of interest to you.

At http://www.controlled-trials.com/ , Current Controlled Trials, you
can search a metaregister described as follows:

"The metaRegister of Controlled Trials is a searchable, international
database of ongoing randomised controlled trials in all areas of
healthcare. At present, the mRCT also contains some completed trials.
Offering access to more than 12,500 records, the mRCT is free. "

And another source at http://www.trialscentral.org/ , Tiral Central
says:

"TrialsCentral provides free and confidential access to listing of
clinical trials. TrialsCentral is a resource for anyone seeking
up-to-date information to support informed, evidence-based decision
making.

The CLINICAL TRIALS page now has an easy-to-use database of clinical
trials registers that you can search by health condition and
geographic location of the trials."

I could not search here for "antibiotic" but could search by condition
if that is helpful for you.

And, Tial Match at http://www.trialmatch.com/ also requires free
registration and then will provide:

"TrialMatch: A Free Service of LifeMetrix, Inc.

TrialMatch was designed to assist visitors to find clinical trials for
which they may qualify. Our list of questions is drawn from trial
criteria supplied by or interpreted from sponsoring organizations. As
you move through the matching process, you will notice that the
questions become more detailed.  For this tool to work best for you,
be prepared with the following information:

Stage and site of disease

History of previous therapies

Allergies

History of any other health conditions 
(such as hypertension/high blood pressure, diabetes) "


Lastly, Veritas Medicine offers the following:

"Veritas Medicine is a free confidential resource providing access to
clinical trials and information on treatment options.

  
Use the Veritas Medicine site to: 

Find ongoing clinical trials that match your medical & geographical
search criteria.

Receive Personalized Trial Notification when appropriate new clinical
trials begin enrollment.

Read articles and receive newsletters from physicians at leading
academic medical centers. "

They are avialable here: http://www.veritasmedicine.com/

I trust this answer has provided you with a selection of sites to
research clinical trials of antibiotics. If anything above is unclear,
please do ask for clarification.

Best regards,

-=clouseau-ga=-
rosemary25-ga rated this answer:4 out of 5 stars

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