What is the effect of cholera toxin on cell signaling(hint: cholera
toxin causes constant activation of alpha s G protein)?

Hi am1107:

I'm not sure what you're looking for here in an answer - since you
seem to have already answered your own question...

However, here's a VERY cool page with some great animations:

http://www-celanphy.sci.kun.nl/Bruce%20web/Flash%20Movies.htm

websearcher-ga

I would recommend you look at a book (yes, I actually still use books
from time to time!) called Microbial Pathogenesis published by
Integrated MEdical SCiences and edited by Bruce McClane, ISBN
1-889325-27-9

"Cholera toxin adenosine diphosphate ribosylates the Gs regulatory
protein of the intestinal adenylate cyclase system, which causes this
stimulatory protein to activate continuously adenylate cyclase.  The
resultant rise in intestinal cyclic adenosine monophosphate (cAMP)
levels then leads to a massive loss of fluid and electrolytes from the
intestines."

This book has a whole bunch more on page 315 and 316.

Cholera bacteria produce cholera toxin, which enters cells lining the
intestine and binds to G-alpha protein subunits.  This prevents a
particular G-alpha from hydrolyzing GTP and leaves this G-alpha in a
perpetually active state. The target of this particular G-alpha is a
sodium ion channel; keeping this G-alpha active causes a continual
outflow of sodium and water into the gut, producing diarrhea and
dehydrating the person.

I tried to put that answer (above) in the answer section... but it didn't work...

Interfers with the phosphodiesterase/cAMP cycle and associated kinase reactions.