Hello Quefix,
Did you suffer any of the following symptoms? ?Cough. Laboured
breathing. Headache. Dry throat. Nasal congestion.? If not, its
likely you experienced a small exposure, that quickly reversed itself.
When you say you felt weird in your chest, it could have been an
allergic reaction. Does your lab have a safety manual on how to deal
with chemical exposures?
http://hazard.com/msds/mf/cards/file/0502.html
Sodium dodecyl sulphate is also known as sodium lauryl sulfate and
SDS, among other names, and from my research, I would not consider
your one time exposure to be particularly serious. Were you seen and
treated by an occupation health or ER physician after your exposure?
It seems SDS is not carcinogenic, or particularly toxic in small
quantities. If you are asthmatic, or suffer from other respiratory
problems, SDS may irritate your lungs more so than ?normal? people.
?May cause allergic respiratory reaction.
? Causes sneezing. do not inhale.
? The sodium salt of dodecyl sulphate has been reported to cause pulmonary
sensitisation resulting in hyperactive airway dysfunction and pulmonary
allergy accompanied by fatigue, malaise and aching. Significant symptoms
of exposure can persist for more than two years and can be activated by a
variety of non-specific environmental stimuli such as automobile exhaust,
perfumes and passive smoking.?
If you have become sensitized, you will have to be particularly
careful NOT to inhale SDS again, as you may suffer a severe allergic
reaction the next time.
http://physics.slss.ie/downloads/ph_sd_md_lauroylsulfate.pdf
This MSDS sheet says the following:
MSDS Name: Sodium dodecyl sulfate
Catalog Numbers: AC226141000, AC226145000, AC230421000, AC230425000,
AC419530010, AC419530250, AC419531000, S799941, S799942, BP166-100,
BP166-5, BP166-500, NC9973507, O2674-25, S529-3, S529-500
Synonyms: SDS; Sodium lauryl sulfate; Dodecyl sodium sulfate; Sulfuric
acid monododecyl ester, sodium salt; SLS; Dodecyl hydrogen sulfate
sodium salt.
Inhalation: Causes respiratory tract irritation. May cause severe
allergic respiratory reaction. May cause severe irritation of the
respiratory tract with sore throat, coughing, shortness of breath and
delayed lung edema.
Chronic: Repeated exposure may cause allergic respiratory reaction
(asthma). Chronic inhalation may lead to decreased pulmonary function.
Inhalation: Get medical aid immediately. Remove from exposure and move
to fresh air immediately. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen.
Notes to Physician: Treat symptomatically and supportively.
Carcinogenicity:
CAS# 151-21-3: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
http://www.glue.umd.edu/~choi/MSDS/Fisher/Sodium%20dodecyl%20sulfate.htm
It appears that the IARC, NIOSH, NTP, and OSHA considers sodium
dodecyl sulfate non-carcinogenic.
From UNEP Chemicals, the center for all chemicals-related activities
of the United Nations Environment Programme:
?SDS is used as a surfactant in detergents, dispersants, cosmetics and
toiletry. SDS is classified as "readily biodegradable" with "low
bioaccumulation". The most sensitive environmental species to SDS is
the clam Corbicula fluminea (30d-NOEC = 0.65 mg/l).
All relevant toxicity endpoints are covered. SDS is a substance of low
toxicity. The substance did not induce mutations in different test
systems. The lowest NOAEL was established for repeated dose toxicity,
being 100 mg/kg bw/day.?
?A safety margin for worst case human exposure (children) of > 600 was
established in the risk assessment. Taking into account the quality
and quantity of the toxicological data and the kind of health effects
observed (mild hepatotoxicity), a safety margin of > 600 is considered
sufficient. Therefore, it is concluded that sodium dodecyl sulfate is
of no concern with respect to human health.?
http://www.chem.unep.ch/irptc/sids/OECDSIDS/151213.htm
?Sodium Lauryl Sulphate Dr. Cole Woolley, B.Sc., Ph.D. Sodium Lauryl
Sulphate Sodium Lauryl Sulfate(SLS), also known as Sodium Dodecyl
Sulphate (SDS), is an anionic surfactant that is one of the most
commonly used chemicals in car wash soaps, garage floor cleaners and
engine degreasers.
Surprisingly, this compound is also found in shampoos, soaps, and
toothpastes. Anionic surfactants are the most common class of
surfactants used in household, personal and industrial cleaners. This
is because of their ability to solubilize fats and oils, lower the
surface tension of aqueous solutions, or form micro emulsions.
Inhaled
Inhalation not likely as material is in needle form.?
http://www.natura.org.uk/health.htm
? ?Carcinogenic nitrosamines can form in the manufacturing of sodium
lauryl sulfate or by its inter-reaction with other nitrogen-bearing
ingredients within a formulation utilizing this ingredient.
? Other studies have indicated that sodium lauryl sulfate enters and
maintains residual levels in the heart, liver, lungs and brain from
skin contact. This poses the question whether it could be a serious
potential health threat from its use in shampoos, cleansers, and
toothpastes.
? Still other research has indicated sodium lauryl sulfate may be
damaging to the immune system, especially within the skin. Skin layers
may separate and inflame due to its protein denaturing properties.
? Although sodium lauryl sulfate is not carcinogenic in experimental
studies, it has been shown that it causes severe epidermal changes in
the area it is applied, indicating a need for tumor-enhancing assays.
? Additional studies have found that sodium lauryl sulfate is heavily
deposited on the skin surface and in the hair follicles. Damage to the
hair follicle could result from such deposition.
http://www.aubrey-organics.com/about/articles/shampoo.cfm
?? S LS is routinely used in clinical studies to irritate skin tissue.
? SLS corrodes hair follicle and impairs ability to grow hair.
? Carcinogenic Nitrates can form when SLS interacts with other
nitrogen bearing ingredients.
? SLS enters and maintains residual levels in the heart, liver, lungs
and brain from skin contact. (Shampoos?)
? SLS denatures protein, impairs proper structural formation of young
eyes - damage permanent.
? SLS can damage the immune system; cause separation of skin layers
and cause inflammation to the skin.?
http://antiagingchoices.com/harmful_ingredients/sodium_lauryl_sulfate.htm
?WARNING! HARMFUL IF SWALLOWED OR INHALED. CAUSES IRRITATION TO SKIN,
EYES AND RESPIRATORY TRACT. MAY CAUSE ALLERGIC SKIN OR RESPIRATORY
REACTION. FLAMMABLE SOLID.?
Follow the following advice to prevent future inhalations:
?8. Exposure Controls/Personal Protection Airborne Exposure Limits:
None established.
Ventilation System:
A system of local and/or general exhaust is recommended to keep
employee exposures as low as possible. Local exhaust ventilation is
generally preferred because it can control the emissions of the
contaminant at its source, preventing dispersion of it into the
general work area. Please refer to the ACGIH document, Industrial
Ventilation, A Manual of Recommended Practices, most recent edition,
for details.
Personal Respirators (NIOSH Approved):
For conditions of use where exposure to the dust or mist is apparent,
a half-face dust/mist respirator may be worn. For emergencies or
instances where the exposure levels are not known, use a full-face
positive-pressure, air-supplied respirator. WARNING: Air-purifying
respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab
coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection:
Use chemical safety goggles. Maintain eye wash fountain and
quick-drench facilities in work area.?
http://www.jtbaker.com/msds/englishhtml/s3670.htm
?Components with Occupational Exposure Limits:
The product does not contain any relevant quantities of materials with
critical values that have to be monitored at the workplace.
Additional information: The lists that were valid during the creation
were used as basis.
Personal protective equipment
General protective and hygienic measures
Keep away from foodstuffs, beverages and feed.
Immediately remove all soiled and contaminated clothing?
http://www.promega.com/msds/us/h5114(USA).pdf
?ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its
aerosol, through the skin and by ingestion.?
http://www.inchem.org/documents/icsc/icsc/eics0502.htm
?Guinea pigs were exposed for thirty minutes to a particulate aerosol
of sodium lauryl sulfate at concentrations of 17.3, 28.9 and 48.6
mg/m3. The exposure chamber in which individual guinea pigs were
exposed was fitted with a microphone to record coughing. As the
concentration of sodium lauryl sulfate increased, the combined number
and severity of the coughs increased and a fade in the response was
also observed with exposure duration.?
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7185614&dopt=Abstract
Constant, repeated exposure CAN indeed be harmful:
?Workers exposed to steam containing SODIUM LAURYL SULFATE have
suffered lung damage and an increased risk of throat cancer.
? It can also be absorbed through skin contact.
? This chemical is used in these types of products:
Toothpaste, Shampoo, Body Wash/Cleanser, Facial Cleanser,
Exfoliant/Scrub, Moisturizer, Hair Color and Bleaching, Foot
Treatment, Liquid Hand Soap, Mouthwash, Bubble Bath, Acne Treatment,
Foundation, Facial Moisturizer/Treatment, Shaving Cream (Men's), Bath
Oil/Salts/Soak, Bar Soap, Tooth Whitening, Relaxer, Pain/Wound
Treatment, Nail Treatment, Conditioner, Depilatory, Eye Liner,
Anti-itch/rash Cream, Skin Fading/Lightener, Anti-aging, Facial Hair
Bleach, Lip Balm/Treatment, Eye Makeup Remover, Mascara, Contact Lens
Cleaners, Body Scrub, Hormonal Cream, Concealer, After Shave?
http://www.natural-skincare-authority.com/SODIUM-LAURYL-SULFATE.html
?SODIUM LAURYL SULFATE
The greatest concern of many scientists is centered around SLS, a
detergent found in approximately 90% of commercial shampoos, including
"no more tears" baby shampoos.
A study has shown that:
? shampoos (with SLS) could retard healing and keeps children's eyes
from developing properly, children under six are especially vulnerable
to improper eye development (Summary of Report of Research to Prevent
Blindness, Inc. Conference.)
? SLS can cause cataracts in adults and delays the healing of wounds
in the surface of the cornea
? SLS builds up in the heart, liver, lungs and brain and can cause
major problems in these areas
? SLS causes skin to flake and to separate and causes substantial
roughness on the skin
? SLS causes dysfunction of the biological systems of the skin
? SLS is such a caustic cleanser that it actually corrodes the hair
follicle and impairs its ability to grow hair
? SLS is routinely used in clinical studies to deliberately irritate
the skin so that the effects of other substances can be tested
http://www.nb.net/~ginesis/g-defs.htm
More MDS data:
http://www.chrismanual.com/D/DDS.pdf
It seems that SDS certainly is an irritant, and can cause allergic
reaction and/or dermatitis in some, from occupational exposure as well
as household products. If you were not checked by a physician at the
time of exposure, I urge you to visit your doctor. I can?t say for
sure if you suffered lasting damage, but it does not seem likely. Your
doctor can order PFTs (Pulmonary function tests) if it appears you
have suffered any damage.
I hope this has adequately answered your question. If not, please
request an Answer Clarification, and allow me to respond, before you
rate this answer. I will be happy to assist you with this question
further, before you rate my answer.
Sincerely, Crabcakes
Search Terms
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Sodium dodecyl sulphate + dangers + inhalation
SDS + lung damage
Sodium dodecyl sulphate + exposure + inhalation
Sodium Lauryl Sulfate + lung damage
Sodium Lauryl Sulfate + inhalation |
