I've received a Doxycycl HYC perscription to treat Lyme Disease. I've
been drinking 2-3 glasses red wine with dinner daily for 2 years.
Question: I've stopped drinking wine since the drug was perscribed,
but I've heard my liver may be in a high-metabolize mode and may
metabolize the Doxycycline too quickly. Is there a period of time I
should wait before beginning the Doxy treatment? Why or why not?

david...

This page from Jackson Gastroenterology notes:

"There are no interactions with alcohol, but combining doxycycline
 and alcohol should be avoided if you have active liver disease."
http://www.gicare.com/pated/doxycycline.htm

More to the point of your question, this page from Life Extension
Drugs notes:

"Alcoholics may have reduced blood levels of doxycycline. This is
 because in this group of people alcohol stimulates the liver to
 metabolise the doxycycline. Alcohol has not been found to have
 this effect in people who drink moderately."
http://www.life-extension-drugs.com/doxycycline.html

2-3 glasses of wine with a meal falls within the definition of
moderate drinking, according to this article from the SelfHelp
Magazine website:
http://www.selfhelpmagazine.com/articles/atd/moderate.html

Additionally, the ease with which you discontinued your daily
consumption suggests that you have not been consuming alcohol
to the point where your liver has suffered and is functioning
abnormally.

sublime1-ga


Additional information may be found from an exploration of
the links resulting from the Google searches outlined below.

Searches done, via Google:

Doxycycline OR "Doxycycl HYC" alcohol
://www.google.com/search?q=Doxycycline+OR+%22Doxycycl+HYC%22+alcohol

moderate drinking
://www.google.com/search?q=moderate+drinking