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Q: Writing a report ( No Answer,   0 Comments )
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Subject: Writing a report
Category: Science > Biology
Asked by: rmorgan-ga
List Price: $9.50
Posted: 13 Jun 2006 17:42 PDT
Expires: 13 Jul 2006 17:42 PDT
Question ID: 737936
What is the minimum lethal dose of synthetic liothyronine sodium (T3)
taken orally?  They typical ranges would be fine as well.

Request for Question Clarification by pafalafa-ga on 13 Jun 2006 18:11 PDT
Liothyronine sodium is administered in very small doses, typically
starting at only 5 micrograms per day, and gradually increased in some
patients.

Individual tablets are usually provided in either 5, 10 or 50
microgram sizes.  The maximum dose for a patient rarely exceeds 100
micrograms/day.

Tolerance to the drug is highly variable in patients, and there is no
reliable information on what constitutes a typical toxic dose.  But
popping multiple pills of the stuff beyond a normal dose would be very
unwise, and quite possibly fatal.


Is that the sort of information you're looking for?


pafalafa-ga

Clarification of Question by rmorgan-ga on 14 Jun 2006 11:40 PDT
Not quite...

In any confirmed cases of death from liothyronine sodium was there a
typical range involved?

I've seen reports of people consuming 150mcg/day with limited side
effects.  I'd like to find in fatal cases what the dose is, and if
there is any MLD or LD information.

Thank you,
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