Lotion vs cream; I think lotion is better and want to find out.
Do people prefer lotion over cream?
If so, why?
What are the findings of surveys and studies say? 
Please cite all surveys and references in your answer.

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Request for Question Clarification by czh-ga on 15 Jun 2006 13:41 PDT

Hello carbon400-ga,

Please tell us more about what you're looking for? What functionality
products are you interested in, i.e., lotions or creams for cosmetics,
medical use, mechanical applications, etc.? The more you can tell us
about the context of your question, the greater the likelihood that we
can get you the information you need. Thanks.

~ czh ~

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Clarification of Question by carbon400-ga on 20 Jun 2006 06:58 PDT

I am researching a lotion being used for medical purposes. If you can
find medical-based information showing lotions are better than creams,
that would be excellent. However, any general information
demonstrating the benefits of lotions over cream would be very very
useful as well.

Thanks,

DVH

Hello DVH,

Below you will find a number of medical references showing that lotion
is more effective or beneficial than cream.


Metronidazole lotion obtained a 0.1% greater efficacy than
Metronidazole cream in the following study.

?Dermatologists treating rosacea may select from a variety of topical
agents. Metronidazole, an effective and commonly used therapy, is
available in several formulations and doses. In this study, there was
no statistically significant difference between efficacies for
metronidazole cream and gel formulations in non-weighted analysis. The
lotion had incrementally (0.1%) greater efficacy than the cream, a
finding limited by the one available RCT of the lotion formulation. In
the weighted analysis, the lotion performed better than the cream and
gel, but without access to primary data, no statistical conclusions
may be drawn from weighted data.?

Journal of Drugs in Dermatology,  April, 2006  by Jane Yoo,  David C.
Reid,  Alexa B. Kimball
http://www.findarticles.com/p/articles/mi_m0PDG/is_4_5/ai_n16361307/pg_4


===================================


J Drugs Dermatol. 2005 May-Jun;4(3):330-6. 
Clobetasol propionate 0.05% lotion in the treatment of moderate to
severe atopic dermatitis: a randomized evaluation versus clobetasol
propionate emollient cream.
Dermatology Clinical Research Institute, Cincinnati, OH, USA.


Clobetasol propionate lotion offers a better remission profile in the
treatment of moderate to severe AD as compared to clobetasol
propionate emollient cream.

Abstract 


?Atopic dermatitis (AD) is a chronic inflammatory and pruritic skin
disorder marked by alternating periods of relapse and remission. This
multicenter, randomized, active- and vehicle-controlled,
investigator-blinded study compared the efficacy and safety of
clobetasol propionate lotion to clobetasol propionate cream
formulation and lotion vehicle in the treatment of moderate to severe
AD. A total of 229 subjects applied treatment twice-daily for 2 weeks.
Clobetasol propionate lotion was significantly more effective than its
lotion vehicle at 2 weeks and comparable to the cream formulation.
Clinical success after a 2-week, treatment-free follow-up period was
greater in the clobetasol propionate lotion group than in the cream
group. Clobetasol propionate lotion is effective, safe, well tolerated
and offers a better remission profile in the treatment of moderate to
severe AD as compared to clobetasol propionate emollient cream.?

PubMed - indexed for MEDLINE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15898289&query_hl=3&itool=pubmed_DocSum


===================================


J Dermatolog Treat. 2005 Aug;16(3):158-64.
Clobetasol propionate lotion, an efficient and safe alternative to
clobetasol propionate emollient cream in subjects with moderate to
severe plaque-type psoriasis.
Clinical Research Specialists, Santa Monica, CA, USA.


OBJECTIVE:
?To assess the efficacy, safety and remission profile of clobetasol
propionate lotion compared to that of clobetasol propionate emollient
cream and lotion vehicle in subjects with moderate to severe
plaque-type psoriasis.?

RESULTS: 
?A total of 192 subjects were treated: 82 with clobetasol propionate
lotion, 81 with clobetasol propionate cream and 29 with the vehicle.
Clobetasol propionate lotion was significantly more effective than
vehicle lotion and was comparable in efficacy to the emollient cream
after 4 weeks of treatment. Treatment success was higher for subjects
in the clobetasol propionate lotion group than in the emollient cream
group after 4 weeks of a treatment-free follow-up period. Clobetasol
propionate lotion was safe and well tolerated.?

CONCLUSION: 
?The present study demonstrates that clobetasol propionate lotion is
an efficacious, safe and well-tolerated alternative to the currently
available emollient cream formulation, while showing a better
remission profile after 4 weeks of treatment-free follow-up period.?

[PubMed - indexed for MEDLINE]
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16096182&query_hl=3&itool=pubmed_docsum



===================================


Am J Clin Dermatol. 2003;4(4):221-4.
Patients' vehicle preference for corticosteroid treatments of scalp psoriasis.
Department of Dermatology, Wake Forest University School of Medicine

Patients with psoriasis generally prefer less messy vehicles, such as
foam and solution preparations, to traditional cream and ointment
vehicles

Abstract

?Topical therapy is one of the foundations of dermatology. The
vehicles used to deliver topical therapy have considerable impact on
efficacy. The vehicle can have direct effects on disease; it can
impact the delivery of the active drug, and its characteristics affect
patient compliance. While the physical chemistry of vehicles has been
studied in great detail, there has been very little study of patients'
preferences for different vehicles and even less on the effect of
these preferences on patient compliance. Such study is essential, as
noncompliance with topical therapy is very common, and likely impacts
the response to topical therapy observed in clinical practice. This
manuscript discusses information on patients' preferences for
different vehicles, focussing on the treatment of scalp psoriasis.
Significant vehicle characteristics such as ease or difficulty of use,
messiness, odors, and staining are recognized to affect patients'
preferences.?

?Patients with psoriasis generally prefer less messy vehicles, such as
foam and solution preparations, to traditional cream and ointment
vehicles. These preferences have the potential to impact patient
compliance.?

?In conclusion, the choice of vehicles impacts both the potency of the
medication and patients' acceptance of the treatment. Actual effects
of different vehicles on compliance are important but have not yet
been adequately studied.?

PubMed - indexed for MEDLINE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12680800&query_hl=3&itool=pubmed_docsum



===================================


Search terms used: 
Lotion  versus cream efficient OR efficiency OR  beneficial OR benefits
Preferences patients lotion cream


I hope the information provided is helpful!

Best regards,
Bobbie7

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Clarification of Answer by bobbie7-ga on 20 Jun 2006 09:48 PDT

"Rosacea patients often prefer lotions over creams as the latter type
of products may increase any shine that tends to be present already."

Rosacea Patients Benefit from New Facial Moisturizer
Source: Dermatology Times
July 1, 2001 
http://mediwire.skyscape.com/main/Default.aspx?P=Content&ArticleID=4359

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Request for Answer Clarification by carbon400-ga on 20 Jun 2006 14:09 PDT

Bobbie7-ga:

Do you have any references to show that fluticasone propionate is
preferred in a lotion instead of a cream? That would be ideal.

Thanks,

DVH

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Clarification of Answer by bobbie7-ga on 20 Jun 2006 14:54 PDT

DVH,

I'll try to find some references regarding fluticasone propionate.

Bobbie7

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Clarification of Answer by bobbie7-ga on 20 Jun 2006 16:40 PDT

Unfortunately I was not able to locate any references showing  that
fluticasone propionate is preferred in a lotion instead of a cream.
http://www.pharmaderm.com/physician_info/cutivate/cutivate_lotion_pi.html


Perhaps this kind of information is scarce because the lotion has only
been introduced recently..

"Atlanta, Georgia ? October 17, 2005 - PharmaDerm today announced the
official launch of CUTIVATE (fluticasone propionate) Lotion, 0.05%,
the only mid-potency steroid lotion approved for patients one year of
age and older.

This newest entry into the market offers dermatologists a
patent-protected mid-potency lotion for their patients? skincare
needs. The new CUTIVATE Lotion treats atopic dermatitis with an
excellent safety profile that includes a low potential to suppress
HPA-axis function, even when used under exaggerated conditions. Also,
CUTIVATE Lotion offers patients an emollient-rich formulation that
relieves symptoms with just once-a-day dosing."
http://www.pharmaderm.com/physician_info/cutivate/cutivate_lotion_pi.html

Cream and ointmet 
"Studies performed with fluticasone propionate cream and fluticasone
propionate ointment indicate that they are in the medium range of
potency as compared with other topical corticosteroids."
http://www.rxlist.com/cgi/generic/flovent_cp.htm

I would suggest you set up an automated PubMed update for new studies
with fluticasone propionate lotion and cream.

Here is the direct link.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed

I hope this helps!

Bobbie7

Unfortunately I was not able to locate any references showing  that
fluticasone propionate is preferred in a lotion instead of a cream.
http://www.pharmaderm.com/physician_info/cutivate/cutivate_lotion_pi.html


Perhaps this kind of information is scarce because the lotion has only
been introduced recently..

"Atlanta, Georgia ? October 17, 2005 - PharmaDerm today announced the
official launch of CUTIVATE (fluticasone propionate) Lotion, 0.05%,
the only mid-potency steroid lotion approved for patients one year of
age and older.

This newest entry into the market offers dermatologists a
patent-protected mid-potency lotion for their patients? skincare
needs. The new CUTIVATE Lotion treats atopic dermatitis with an
excellent safety profile that includes a low potential to suppress
HPA-axis function, even when used under exaggerated conditions. Also,
CUTIVATE Lotion offers patients an emollient-rich formulation that
relieves symptoms with just once-a-day dosing."
http://www.pharmaderm.com/physician_info/cutivate/cutivate_lotion_pi.html

Cream and ointmet 
"Studies performed with fluticasone propionate cream and fluticasone
propionate ointment indicate that they are in the medium range of
potency as compared with other topical corticosteroids."
http://www.rxlist.com/cgi/generic/flovent_cp.htm

I would suggest you set up an automated PubMed update for new studies
with fluticasone propionate lotion and cream.

Here is the direct link.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed

I hope this helps!

Bobbie7