It has been shown that there is a relationship between glaucoma
(and/or intraocular pressure - IOP) and collagen metabolism. It is
also known that there is a link between ascorbic acid and collagen
metabolism. Finally, it has been reported that ascorbic acid "is an
effective adjunct in stabilizing IOP".
For the answer to this question, I would like a detailed explanation
of these relationships, including both a lay person's explanation as
well as medical, physiological and biochemical facts (and some
speculation about possible pathways, relationships, etc. is welcome).
I would like to know if scurvy produces changes in the eye that are
consistent with those seen in elevated IOP/glaucoma. I would like to
know if any research has correlated gum disease (one of the first
signs of scurvy) with glaucoma. Another symptom sometimes related to
scurvy is postural hypotension. At least one study has found some
relationship between glaucoma and nocturnal hypotension. I would like
to understand more about any potential biochemical or physiological
links between postural hypotension, glaucoma and ascorbic acid (and I
can guess that it may be necessary to consider the adrenal glands to
make the connection).
I would like to obtain as much information as possible about the
connection between ascorbic acid, collagen, and glaucoma.
An acceptable answer to this question probably involves more than
simply searching the Internet. (If you intend to answer it just by
searching the same sources I could search on the Internet, then that's
probably not the answer I'm expecting.) I hope I have priced it fairly
and I hope someone has the knowledge or resources to give some good
answers. Thanks. |