Asked by: tina81-ga
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22 Jun 2006 03:56 PDT
Expires: 22 Jul 2006 03:56 PDT
Question ID: 740161
how do sonic hedgehog and brain morphogenic proteins influence spinal cord development?
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From: pinkfreud-ga on 23 Jun 2006 14:02 PDT
This may be of interest to you: http://www.lbl.gov/Science-Articles/Archive/sb/Nov-2004/04-sonicthehedgehog.html
From: tina81-ga on 25 Jun 2006 14:55 PDT
From: txchic-ga on 09 Jul 2006 16:22 PDT
from "Neuroscience" ed. Dale Purves. third edition. sinauer publishers. "Another peptide hormone essential for neural induction is sonic hedgehog (shh). Shh is thought to be particularly important for differentiation of neurons - including motor neurons - in the ventral portion of the neural tube...expression of shh mRNA is limited to the notochord and floorplate of the developing spinal cord. This localized expression is thought to establish a gradient of secreted shh peptide extending throughout most of the ventral spinal cord."
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