Google Answers Logo
View Question
 
Q: L-Carnitine - bioavailability, pharmacokinetics ( Answered 4 out of 5 stars,   0 Comments )
Question  
Subject: L-Carnitine - bioavailability, pharmacokinetics
Category: Health > Fitness and Nutrition
Asked by: saregamapa-ga
List Price: $25.00
Posted: 04 Jul 2006 21:59 PDT
Expires: 03 Aug 2006 21:59 PDT
Question ID: 743429
What is the bioavailability of L-Carnitine in humans upon oral
administrations at low, medium and high dose?  We seek details about
its pharmacokinetics.
Answer  
Subject: Re: L-Carnitine - bioavailability, pharmacokinetics
Answered By: keystroke-ga on 05 Jul 2006 05:33 PDT
Rated:4 out of 5 stars
 
Like most drugs, much of l-carnitine taken orally is lost and not
available to the body. The best method for gaining the highest
absorption rate is to acquire it through the diet, not theough
supplements.  Dietary l-carnitine (from the actual diet) maintains an
absorption rate of 54-87%, dependent on the dosage, from low (54%) to
high (87%), whereas supplementary l-carnitine is passively absorbed
and therefore only maintains a bioavailability of 14-18% of the dose
taken.

Sources:
http://www.annalsnyas.org/cgi/content/abstract/1033/1/30
http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/lca_0060.shtml

Search terms: bioavailability + l carnitine

Let me know if you need any other assistance or any clarification of
this answer. I'd be happy to help!

--keystroke-ga
saregamapa-ga rated this answer:4 out of 5 stars
Good

Comments  
There are no comments at this time.

Important Disclaimer: Answers and comments provided on Google Answers are general information, and are not intended to substitute for informed professional medical, psychiatric, psychological, tax, legal, investment, accounting, or other professional advice. Google does not endorse, and expressly disclaims liability for any product, manufacturer, distributor, service or service provider mentioned or any opinion expressed in answers or comments. Please read carefully the Google Answers Terms of Service.

If you feel that you have found inappropriate content, please let us know by emailing us at answers-support@google.com with the question ID listed above. Thank you.
Search Google Answers for
Google Answers  


Google Home - Answers FAQ - Terms of Service - Privacy Policy