Once the ovum fuses with a single sperm cell, its cell membrane changes - how?
Category: Science > Biology
Asked by: repran-ga
List Price: $10.00
19 Sep 2006 23:42 PDT
Expires: 19 Oct 2006 23:42 PDT
Question ID: 766869
This is for a book project - please answer in as much biochemical details as possible: In human embryogenesis once the ovum fuses with a single sperm cell, its cell membrane changes, preventing fusion with other sperm. How does this happen chemically? I am looking for a chemically accurate and detailed descirption of the process. Information on the complete process starting from sperm-egg attarction/intercation and ending with Mitosis over Meiosis will earn extra points. Thanks, Stefan
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Re: Once the ovum fuses with a single sperm cell, its cell membrane changes - how?
From: dynasty23-ga on 06 Oct 2006 00:35 PDT
After the first sperm passes through the zona pellucida of the ovum, the glycoprotein structure of the zona pellucida is altered, a reaction that is catalyzed by proteases released from cortical granules. This is known as the cortical reaction. Search terms: sperm ovum fusion cell membrane zona cortical reaction polyspermy cortical See: http://188.8.131.52/search?q=cache:yg-HtU9oQAUJ:www.siu.edu/~tw3a/431fert.htm+sperm+ovum+fusion+cell+membrane+zona+reaction+polyspermy&hl=en&gl=us&ct=clnk&cd=1 http://humupd.oxfordjournals.org/cgi/content/abstract/2/1/29 http://ijr.sagepub.com/cgi/content/abstract/24/2-3/211 http://www.answers.com/topic/cortical-reaction http://www.uwyo.edu/wjm/repro/fert.htm http://www.ibscrewed.net/resource/notes/hlbio11.html http://www.annalsnyas.org/cgi/content/abstract/541/1/621 Dynasty
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