Background: If a man becomes castrated, the testosterone drops to
castrate levels, and then osteoporosis develops. However, this usually
does not happen in pre-menopausal women, nor does it happen in
pre-pubertal children. Women normally have a small amount of
testosterone, small enough to cause osteoporosis in a man. But woman
have higher levels of estrogen and progesterone, both of which
counteract osteoporosis. Pre-pubertal children, especially girls, have
very small amounts of testosterone, estrogen, and progesterone, yet
they do no develop osteoporosis. Why?
Question: What is the exact mechanism of osteoporosis in testosterone
deficient man?
Or more importantly, how can osteoporosis be prevented in testosterone
deficient man, without using testosterone, other hormones
(progestogens, estrogens), osteoporosis medications, or osteoporosis
supplements (such as calcium)? |