My thoughts go out to this dog for a full recovery. That said, I
discovered the following on the site
http://www.vetsoftware.com/WVC2002_VET_106.htm in a report titled
"Non-Odontogenic Tumors" by by Frank Verstraete. About a third of the
way down the page is a sub-heading "Squamous cell carcinoma" and it
reads in part:
"Wide or radical excision [this would include amputation] is generally
the treatment of choice for squamous cell carcinoma in the dog. The
one-year survival rate for squamous cell carcinoma following
mandibulectomy and maxillectomy is in the order of 70% and higher,
with a median survival time of 18 months. The prognosis for the
individual patient largely depends on the site, as this determines the
biologic behavior of the tumor as well the technical feasibility of
obtaining tumor-free margins.
"Oral squamous cell carcinoma in the dog is radiosensitive and may be
radiocurative. Small, superficial tumors are good candidates for
radiation therapy, while large tumors with extensive bone infiltration
carry a less favorable prognosis."
I also located this information at Animals Unlimited
(http://animalsunlimited.net/maxdoc14.htm):
"Treatment: Malignant melanomas are highly invasive and metastasize
readily; consequently the prognosis is poor. Surgical resection can
extend the survival time by decreasing local recurrence. which is
frequent. Nontonsillar squamous cell carcinoma is locally invasive
with a low rate of metastasis, and the prognosis is good with
aggressive surgical resection and/or radiation therapy."
This from (http://maxshouse.com/squamous_cell_carcinoma.htm)
"Chemotherapy for cutaneous SCC has shown little consistent efficacy
in the veterinary literature. Agents that have been
investigated on a limited basis for SCC in the dog and cat include
mitoxantrone, actinomycin D, doxorubicin/ cyclophosphamide
combinations, bleomycin, and cisplatin (not used in cats). Response
rates are generally low and short-lived in duration. Chemotherapy in
an adjuvant setting for microscopic disease following surgery or in
conjunction with radiotherapy should be investigated for high-grade
lesions. Intralesional sustained release cisplatin and 5-FU have also
been investigated in dogs, along with local hyperthermia and alone in
cats with superficial SCC. Long-term results are lacking; however,
nearly half of the cats and dogs with actinic-related SCC have
achieved a complete response."
From the first reference I found, oral Squamous Cell Carcinoma (and
nasal) seem to have more a survival rate. I would suggest checking
the dog's mouth and nose to be certain there are not instances of oral
Squamous Cell Carcinoma in those regions as well.
Should you need clarification before rating, please request it. My
positive thoughts are with your canine friend.
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