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Q: Over the counter (OTC) and prescription (Rx) drug deaths ( Answered,   0 Comments )
Question  
Subject: Over the counter (OTC) and prescription (Rx) drug deaths
Category: Health > Medicine
Asked by: saverio-ga
List Price: $140.00
Posted: 02 Jan 2004 16:14 PST
Expires: 01 Feb 2004 16:14 PST
Question ID: 292523
I am a naturopathic physician, if you want to know more about
naturopathic medicine or me see our web site
connecticutcenterforhealth.com.
Question: I want to know specifically what individual OTC drugs and
prescription (Rx) drugs are responsible for deaths each year and the
number of deaths.  For example the answer I would most like to see is
a list of drugs and how many people they are responsible for killing
each year.  To clarify things further if possible leave out stats on
alcohol and tobacco related deaths.  Also, leave out deaths where OTC
and Rx drugs were used by people to commit suicide.  OTC and Rx drug
deaths are usually broken down into deaths as a result of adverse drug
reactions when properly prescribed and deaths caused by improper
prescribing. I have searched the web in several ways and have come up
with zip reagrding the kind of detail I need.  It's as if the
pharmaceutical industry is burying that info deep so it is not readily
accessible and I don't have the time to search and search.  Your help
here is appreciated.
Answer  
Subject: Re: Over the counter (OTC) and prescription (Rx) drug deaths
Answered By: pafalafa-ga on 03 Jan 2004 09:41 PST
 
Hello saverio-ga, and thank you for your question.  This is a topic I
care a great deal about myself, and I appreciate the opportunity to
research it for you.

The most detailed and up-to-date source of information on
medicine-related fatalities is the:

2002 Annual Report of the American Association of Poison Control
Centers:  Toxic Exposure Surveillance System (TESS)

which can found on their web site at:

http://www.aapcc.org/Annual%20Reports/02report/Annual%20Report%202002.pdf


The TESS data for 2002 includes input from 2.38 million poison
exposure cases reported to poison control cases in the United States,
resulting in 1,153 fatalities.  Of course, not all of the exposures
are to medicines, but the report provides very detailed breakouts of
the types of substances involved in TESS exposures, and the outcomes
of the incidents.

According to the TESS data, the following numbers of deaths occurred
in 2002 due to use of over the counter and prescription drugs:

=====

NOTE:  

Information is presented as [ #/# ] where the first number is
unintentional deaths (including therapeutic errors and "unknown"
causes), while the second number is intentional deaths (e.g. suicide,
foul play).  For example, the first entry is:

Acetaminophen..........22/168

indicating 22 unintentional deaths and 168 intentional deaths
associated with acetaminophen exposures.

In cases where more than one substance is involved, the listed
medicine is considered the primary cause of death. Deaths from
narcotics (heroin, cocaine, etc.) are included in the TESS data, but
have not been included here, with the exception of methadone, which is
included in the list, below.

=====

 
ANALGESICS:
Acetaminophen..........22/168
Aspirin.................1/42
Colchicine..............3/2
Fentanyl................1/11
Hyrdocodone.............1/6
Hydromorphone...........1/1
Meperidine..............2/0
Methadone..............11/46
Morphine................6/19
Opiod...................1/2
Oxycodone...............1/26
Pentazocine.............1/0
Propoxaphene............1/1
Tramadol................0/2

ANESTHETICS.............1/2

ANTICHOLINERGICS........0/2

ANTICOAGULANTS
Lepirudin...............1/0
Warfarin................3/0

ANTICONVULSANTS
Carbamarzepine..........0/4
Lamotrigine.............0/3
Phenytoin...............1/1
Topiramate..............0/1
Valproic acid...........1/9
Zonisamide..............0/1

ANTIDEPRESSANTS
Amitriptyline...........4/38
Bupropion...............0/8
Citalopram..............0/4
Clomipramine............0/2
Desipramine.............1/2
Doxepin.................0/20
Fluoxetine..............0/3
Imipramine..............0/5
Lithium.................4/4
Maprotiline.............0/1
Mirtazapine.............0/1
Nortriptyline...........0/5
Paroxetine..............1/2
Sertraline..............0/4
Tranylcypromine (sp?)...0/1
Trazadone...............0/3
Tricyclic antidep.......2/10
Venlafaxine.............1/8

ANTIHISTAMINES

Diphenhydramine.........0/12
Others..................0/2

ANTIMICROBIALS
Amphotericin............1/0
Ciprofloxacin...........1/0
Others..................0/2

ANTINEOPLASTICS
Hydroxyurea methotrexate 1/0
Vincristine..............1/0

ASTHMA MEDICINE
Theophylline.............3/5

CARDIOVASCULAR DRUGS
Acebutolol...............0/1
Amiodarone...............1/0
Amiodipine...............1/7
Atenolol.................0/3
Clonidine................0/3
Digoxin..................9/2
Diltiazem................2/18
Enalapril................0/1
Metoprolol...............1/6
Nifedipine...............2/4
Propafenone..............1/0
Propranolol..............0/7
Verapamil................2/23

COUGH MEDICINE...........3/3

DIETARY SUPPLEMENTS......1/1

DIURETICS................0/1

ELECTROLYTES
Iron dextran.............1/0

GASTROINTESTINAL
PREPARATIONS.............0/1

HORMONES AND HORMONE ANTAGONISTS
Corticosteroid...........1/0
Metformin................6/3
Others...................0/6

MISC.
Disulfiram...............1/0
Quinine..................1/0
Sildenafil...............1/0

MUSCLE RELAXANTS
Cyclobenzaprine..........1/4
Others...................0/11

OTHERS/UNKNOWNS..........4/4

SEDATIVES/HYPNOTICS/ANTIPSYCHOTICS
Alprazolam...............3/13
Barbituate...............0/3
Benzodiazepine...........0/3
Chloral hydrate..........1/2
Clonazepam...............1/2
Clozapine................1/0
Diazepam.................4/3
Haloperidol..............1/1
Quetiapine...............1/9
Secobarbital.............1/0
Temazepam................1/3
Others...................0/33

SERUMS, TOXOIDS, VACCINES
Antivenom................1/0


==========

Table 22B of the TESS report contains additional details about total
exposures as reported to poison control centers, for pharmaceutical
products (Table 22A reports similar information for
non-pharmaceuticals, such as oven cleaner).

The information for adult-formulation acetaminophen, for example, looks like this:

Number of exposures.......29,967
Unintentional.............14,455
Intentional...............15,043
Other.........................12
Adverse Reaction.............328
Rec'd medical treatment...17,349

OUTCOMES:
None.......................8,237
Minor......................4,593
Moderate...................2,313
Major........................586
Deaths........................63

The data also includes age breakdowns number of incidents for children
under 6 years old; 6-19 year olds; and over 19 years of age.


==========

The TESS data presents a highly-detailed look at poisoning incidents
and fatalities from over the counter and prescription drugs.  However,
the several hundred deaths reported from specific medications only
represent the proverbial tip of the iceberg for medicine-related
deaths.

In 2000, Dr. Barbara Starfield of Johns Hopkins School of Hygiene and
Public Health published a seminal paper in the Journal of the American
Medical Association entitled:  "Is US Health Really the Best in the
World?" (JAMA July 26, 2000 pg. 483).  In the paper, she reports that
iatrogenic (doctor-caused) deaths are one of the leading causes of
death in the United States, and annually include:

12,000 deaths from unnecessary surgery
7,000 deaths from medication errors
20,000 deaths from other medical errors
80,000 deaths from nosocomial infections in hospitals

and an astounding

106,000 deaths per year from adverse reactions to medications that
were not administered in error.

The adverse reaction figure of 106,000 deaths per year comes from an
earlier, important study, also published in JAMA:

-----

Incidence of adverse drug reactions in hospitalized patients: A
meta-analysis of prospective studies

Jason Lazarou et al JAMA Apr 15, 1998 p. 1200


The article has one of the briefest, most understated abstracts I've ever seen:

"A study was conducted to estimate the incidence of serious and fatal
adverse drug reactions (ADRs) in hospital patients. The incidence of
serious and fatal ADRs in US hospitals was found to be extremely
high."

-----

Neither the Starfield nor the Lazarou articles provide details on
deaths from individual drugs; rather, they provide broad overviews
based on numerous studies of ADRs among individual groups of patients.

However, their work makes clear that the scale of adverse reactions to
medications is one of the leading causes of death in the United
States.

I hope this information fully meets your needs.  But if anything here
is unclear -- or if you need additional information -- let me know by
posting a Request for Clarification, and I'll be happy to assist your
further in your most interesting search for information.

pafalafa-ga


search strategy:  Google searches on:  
pharmaceutical deaths ("hospital error" OR "medical error")
Starfield iatrogenic
TESS "annual report"

Request for Answer Clarification by saverio-ga on 04 Jan 2004 14:16 PST
Just saw your answer.  Evereything you posted I already knew about. 
What I want to know for instance is the breakdown of the 106,000
deaths that were caused by adverse events from properly prescribed
drugs.  What drugs caused what # of deaths. The TESS numbers are
laughable in the face of 106,000 deaths.  "what drugs" caused those
106,000 deaths specifically?  And... what drugs caused the X number of
deaths where drugs where improperly prescribed/medical mistakes were
made.  Thank you for your effort but your answer does not supply me
with what I requested.  Please keep trying.  I am willing to pay you
well for the answer but I doubt you spent much time finding what you
reported.  Did you?  Please advise.

Clarification of Answer by pafalafa-ga on 04 Jan 2004 16:58 PST
You asked me to "please advise" about how I came to my answer, and I
am happy to do so.

Yes, I spent a considerable amount of time researching and preparing
your answer, as would be appropriate for a question priced at a fairly
high level.

The TESS data, in particular, took a lot of massaging to present it in
the way I did.  The original report presents individual incident
report data, rather than consolidated data, and does not provide any
simple way to summarize the data on individual medicines.

It's too bad the answer didn't meet your needs.  

I also looked for information that would allow a breakdown of the
106,000 adverse reaction deaths, and the 7,000 medicine mistake
deaths, but did not find it...the methodology of the two studies I
referenced and reviewed did not allow for characterizations of the
contribution of individual medicines.

Possibly, such numbers could be partially extracted from the extensive
literature on ADRs.  However, since your question indicated that you
had, in your own search for information, "come up with zip" -- I
thought the information I was providing to you would be informative
and useful, as well as fully responsive to your question.

The TESS data and the papers I referenced may have been self-evident
to you, but as I am search specialist rather than a medical
specialist, it took a fair amount of searching various sources to even
locate these primary sources of information.

So...what next?

It is always possible for me to ask the editors at GA to remove my
answer, so that another researcher could have a crack at it.  Perhaps,
now that the parameters of the question are clearer, someone could do
the type of deep analysis of the literature you seem to be seeking.

Is that your wish?

Request for Answer Clarification by saverio-ga on 04 Jan 2004 17:07 PST
I wish to have the answers I seek.  Can you find them?  If so, how
much time might it take?  I don't want to put someone else on this as
we'd probably end up at the same place. The question I ask "Is the
info out there"?  Are you willing to work further and at what cost? 
Let's dicker...  Let me know.

Clarification of Answer by pafalafa-ga on 04 Jan 2004 20:09 PST
>>I wish to have the answers I seek.<<

As you should...that's the whole purpose of GA

>>Can you find them?<<

If the information is out there, I probably can.  If it's not, I can't.

>>If so, how much time might it take?<<

Probably about 3 hours to review the ADR literature to determine if
the information exists, another 2 or 3 to extract it if it does, and 2
or 3 more to write it up.  Doing the same for the medication errors
information would take about the same degree of effort, even though
the overall number of deaths is much smaller (106,000 vs 7,000).

>>I don't want to put someone else on this as we'd probably end up at
the same place.<<

Maybe, maybe not.  Even if my answer is withdrawn, I can post it as a
comment so other researchers will know the history on this, and can
therby avoid taking the same approach I did.

I have a background in epidemiology, so I'm fairly comfortable with
the type of literature involved.  But there are two or three other
researchers at GA that I'm aware of who have fairly comprehensive
medical backgrounds.  I'll invite any of them who may be reading this
exchange to post a comment here if they feel they can tackle this
question, or otherwise have an opinion on its answerability.

>>The question I ask "Is the info out there"?<<

Actually, that's just one of several.  But the answer is still "Maybe
yes, maybe no...I can't know until I look"

>>Are you willing to work further and at what cost? Let's dicker.<<

I've got no problem with the dickering part.  But I don't want to put
myself in a situation of doing hours upon of hours of work, only to
find that I can't offer you an answer because there is none to be had.

Unfortunately, the GA system -- where the researcher is paid only if
an answer is posted, and it's 100% satisfactory to the client --
doesn't really lend itself very well to resolving these types of
situations.

I think that for us to find a resolution that works well for both of
us will probably take a round or two more of these type of exchanges. 
If you're willing to invest the effort, let me know your thoughts on
the situation.  I'd especially like to hear any ideas you may have
about how to best move forward on this.

Thanks.

pafalafa-ga

Request for Answer Clarification by saverio-ga on 07 Jan 2004 16:12 PST
Been busy so no response, back now.  Instead of going back and forth
here, can we speak on the phone?  I would prefer that.  If not, I
request that you give me an hourly rate you are comfortable with and
we'll set an hour limit not to exceed and see where you can get.  Let
me know.

Clarification of Answer by pafalafa-ga on 07 Jan 2004 17:00 PST
Hello again,

The rules at Google Answers don't allow contact between researchers
and clients other than here in this public form, so I'm afraid a phone
call is not in the cards (which is too bad sometimes...this is one
case where it would simplify things).

Why don't we proceed like this:

--Post another question in an amount you're comfortable with.  I'll
suggest $100, but any number that works for you is OK (the maximum
price allowed is $200).

--Keep the wording of the question fairly open-ended.  That is, ask
for a review and summary of the literature on XYZ, to include a list
of ADRs for specific drugs *if known*.  Youve already made clear what
you're seeking at this point, so the question is just to set the
parameters of price, and to make it clear that it would be acceptable
to not list specific drugs if such information is not available.

--If you'd like, you can direct the question specifically to my
attention (e.g., in the "subject" line, put "For pafalafa-ga").  Or if
you prefer, leave it open for anyone to tackle.

--I'll work the question at a rate of about $25/hr (cheap!), and then
provide my findings as an answer.

--Bear in mind:  you must be satisifed with the answers you get here,
or you are absolutely entitled to a full refund.  Nothing about our
arrangement would change that fundamental rule.

Look forward to hearing back from you.

paf

Request for Answer Clarification by saverio-ga on 16 Jan 2004 17:37 PST
paf
Sorry for delay.  Was away, busy, overwhelmed.  I'll post another
question to you within the parameters you suggested.  Will post over
the weekend.

Clarification of Answer by pafalafa-ga on 16 Jan 2004 17:58 PST
Hello Doc,

Nice to hear from you.  

Take a deep breath, and post a new question when you're ready.  I'll
do my best to dig up the information you're looking for.

Best...

pafalafa-ga

Request for Answer Clarification by saverio-ga on 07 Feb 2004 17:33 PST
pafalafa
Been distracted as you can see.  Want to continue as you suggested in
last post.  Want you to frame question that I can then post asking you
to do it.  Did you get paid?  Let me know...

Request for Answer Clarification by saverio-ga on 07 Feb 2004 17:34 PST
Question?  I didn't cuase any problems for you by not rating the
answer did I?  Let me know...

Clarification of Answer by pafalafa-ga on 07 Feb 2004 18:13 PST
Hi.  Nice to hear back from you again.  

You asked:  >>I didn't cause any problems for you by not rating the
answer did I?<<

No problem at all.  Positive ratings are always welcome; negative
ratings, although painful, are instructional.  But nothing in
particular is expected from you by way of follow-up to an answer.

Once a question is answered, no further action is required on your
part, although there are several *optional* follow-ups at your
disposal.  You can:

--ask for clarification
--post a comment
--provide a rating
--offer a tip
--request a refund

And of course, you can post a new question (or questions).  On that
front, here is a suggestion for a follow-on question you can post:

==========

Subject:  A question for pafalafa-ga

It's been estimated that more than 100,000 deaths per year are due to
adverse reactions to medications, both Rx and OTC.  I would like you
to review the literature on these deaths and summarize for me -- as
quantitatively as possible -- what causes these deaths (e.g.
unanticipated reactions vs medical errors), and the particular drugs
that appear to be responsible. Note that I am not looking for
information on alcohol, tobacco or intentional overdoses, however.

I understand that hard numbers may not exist for individual drugs, but
I would like you to do the best you can, as diligently as you can, for
the fee provided.

==========

Of course, feel free to tinker/change/ignore this suggested language
if something else better suits your needs.  As I said, I'm willing to
put in a good effort at a rate of about $25/hr.  Please don't be in a
rush, however, as I suspect I will need a good chunk of time to "clear
the decks" and focus on your follow-up question.

I look forward to hearing back from you.  

pafalafa-ga

Clarification of Answer by pafalafa-ga on 05 Dec 2006 06:52 PST
Here's a list of over-the-counter drugs (medicines) listed in the
FDA's Orange Book -- the list includes both generic and trade names
for the medicines:



OTC Drugs and Medicines in FDA's Orange Book:


ABREVA
ACEPHEN
ACETAMINOPHEN
ACETAMINOPHEN, ASPIRIN AND CAFFEINE
ACETAMINOPHEN; ASPIRIN; CAFFEINE
ACETAMINOPHEN; CLEMASTINE FUMARATE; PSEUDOEPHEDRINE HYDROCHLORIDE
ACETAMINOPHEN; DEXBROMPHENIRAMINE MALEATE; PSEUDOEPHEDRINE SULFATE
ACTRON
ADVIL
ADVIL ALLERGY SINUS
ADVIL COLD AND SINUS
ADVIL LIQUI-GELS
ADVIL MIGRAINE LIQUI-GELS
AFRINOL
ALAVERT
ALCOHOL; CHLORHEXIDINE GLUCONATE
ALEVE
ALEVE COLD AND SINUS
ALUMINUM HYDROXIDE; MAGNESIUM TRISILICATE
ANTAZOLINE PHOSPHATE; NAPHAZOLINE HYDROCHLORIDE
ASPIRIN
AVAGARD
AVOBENZONE; OCTINOXATE; OXYBENZONE
AXID AR
BAYER EXTRA STRENGTH ASPIRIN FOR MIGRAINE PAIN
BENTOQUATAM
BIOSCRUB
BRIAN CARE
BROMPHENIRAMINE MALEATE; PSEUDOEPHEDRINE HYDROCHLORIDE
BRONCHO SALINE
BRONITIN MIST
BUTENAFINE HYDROCHLORIDE
BUTOCONAZOLE NITRATE
CALCIUM CARBONATE, PRECIPITATED; FAMOTIDINE; MAGNESIUM HYDROXIDE
CAP-PROFEN
CHG SCRUB
CHILDREN'S ADVIL
CHILDREN'S ADVIL ALLERGY SINUS
CHILDREN'S ADVIL COLD
CHILDREN'S ADVIL-FLAVORED
CHILDREN'S ELIXSURE
CHILDREN'S IBUPROFEN
CHILDREN'S MOTRIN
CHILDREN'S MOTRIN COLD
CHLORAPREP ONE-STEP FREPP
CHLORAPREP ONE-STEP SEPP
CHLORAPREP WITH TINT
CHLORHEXIDINE GLUCONATE
CHLORHEXIDINE GLUCONATE; ISOPROPYL ALCOHOL
CHLORPHENIRAMINE MALEATE
CHLORPHENIRAMINE MALEATE; IBUPROFEN; PSEUDOEPHEDRINE HYDROCHLORIDE
CHLORPHENIRAMINE MALEATE; PSEUDOEPHEDRINE SULFATE
CHLOR-TRIMETON
CIDA-STAT
CIMETIDINE
CLARITIN
CLARITIN HIVES RELIEF
CLARITIN HIVES RELIEF REDITAB
CLARITIN REDITABS
CLARITIN-D 24 HOUR
CLEMASTINE FUMARATE
CLOTRIMAZOLE
COLGATE TOTAL
COMMIT
CROMOLYN SODIUM
DELSYM
DEXBROMPHENIRAMINE MALEATE; PSEUDOEPHEDRINE SULFATE
DEXTROMETHORPHAN HYDROBROMIDE; GUAIFENESIN
DEXTROMETHORPHAN POLISTIREX
DISOPHROL
DOCOSANOL
DOXYLAMINE SUCCINATE
DRIXORAL
DRIXORAL PLUS
DYNA-HEX
EFIDAC 24 PSEUDOEPHEDRINE HCL
EFIDAC 24 PSEUDOEPHEDRINE HCL/BROMPHENIRAMINE MALEATE
EPINEPHRINE
EPINEPHRINE BITARTRATE
EXCEDRIN (MIGRAINE)
EXIDINE
EXTRA-STRENGTH AIM
E-Z PREP
E-Z PREP 220
E-Z SCRUB 201
E-Z SCRUB 241
FAMOTIDINE
FEMSTAT 3
FOAMCOAT
GAVISCON
GUAIFENESIN
GUAIFENESIN; PSEUDOEPHEDRINE HYDROCHLORIDE
GYNE-LOTRIMIN
GYNE-LOTRIMIN 3
GYNE-LOTRIMIN 3 COMBINATION PACK
GYNE-LOTRIMIN COMBINATION PACK
GYNIX
HABITROL
HIBICLENS
HIBISTAT
HUMULIN 50/50
HUMULIN 70/30
HUMULIN 70/30 PEN
HUMULIN L
HUMULIN N
HUMULIN R
HUMULIN R PEN
HUMULIN U
IBUPROFEN
IBUPROFEN AND PSEUDOEPHEDRINE HCL
IBUPROFEN POTASSIUM
IBUPROFEN POTASSIUM; PSEUDOEPHEDRINE HYDROCHLORIDE
IBUPROFEN; PSEUDOEPHEDRINE HYDROCHLORIDE
IBUPROHM
IBUPROHM COLD AND SINUS
IBU-TAB 200
IMODIUM A-D
IMODIUM ADVANCED
INFANTS' FEVERALL
INSULIN PURIFIED PORK
INSULIN RECOMBINANT HUMAN
INSULIN RECOMBINANT HUMAN; INSULIN SUSP ISOPHANE RECOMBINANT HUMAN
INSULIN SUSP ISOPHANE BEEF/PORK
INSULIN SUSP ISOPHANE PURIFIED PORK
INSULIN SUSP ISOPHANE RECOMBINANT HUMAN
INSULIN ZINC SUSP EXTENDED RECOMBINANT HUMAN
INSULIN ZINC SUSP PURIFIED PORK
INSULIN ZINC SUSP RECOMBINANT HUMAN
IOSAT
IVY BLOCK
JUNIOR STRENGTH ADVIL
JUNIOR STRENGTH IBUPROFEN
JUNIOR STRENGTH MOTRIN
KETOCONAZOLE
KETOPROFEN
LAMISIL
LAMISIL AT
LENTE ILETIN II (PORK)
LOPERAMIDE HCL
LOPERAMIDE HCL AND SIMETHICONE
LOPERAMIDE HYDROCHLORIDE
LOPERAMIDE HYDROCHLORIDE; SIMETHICONE
LORATADINE
LORATADINE AND PSEUDOEPHEDRINE SULFATE
LORATADINE; PSEUDOEPHEDRINE SULFATE
LOTRIMIN ULTRA
MEDIPREN
MICONAZOLE 3
MICONAZOLE 3 COMBINATION PACK
MICONAZOLE 7
MICONAZOLE 7 COMBINATION PACK
MICONAZOLE NITRATE
MICONAZOLE NITRATE COMBINATION PACK
MICRODERM
MINOXIDIL
MINOXIDIL (FOR MEN)
MINOXIDIL (FOR WOMEN)
MINOXIDIL EXTRA STRENGTH (FOR MEN)
MONISTAT 1 COMBINATION PACK
MONISTAT 3
MONISTAT 3 COMBINATION PACK
MONISTAT 3 COMBINATION PACK (PREFILLED)
MONISTAT 7
MONISTAT 7 COMBINATION PACK
MONISTAT-3 COMBINATION PACK
MOTRIN IB
MOTRIN MIGRAINE PAIN
MUCINEX
MUCINEX D
MUCINEX DM
MYCELEX-7
MYCELEX-7 COMBINATION PACK
M-ZOLE 3 COMBINATION PACK
M-ZOLE 7 DUAL PACK
NAPHAZOLINE HYDROCHLORIDE; PHENIRAMINE MALEATE
NAPHCON-A
NAPROXEN SODIUM
NAPROXEN SODIUM AND PSEUDOEPHEDRINE HCL
NAPROXEN SODIUM; PSEUDOEPHEDRINE HYDROCHLORIDE
NASALCROM
NEOPAP
NICODERM CQ
NICORETTE
NICORETTE (MINT)
NICORETTE (ORANGE)
NICOTINE
NICOTINE POLACRILEX
NICOTINE POLACRILEX (MINT)
NICOTINE POLACRILEX (ORANGE)
NICOTROL
NIX
NIZATIDINE
NIZORAL A-D
NOVOLIN 70/30
NOVOLIN L
NOVOLIN N
NOVOLIN R
NPH ILETIN I (BEEF-PORK)
NPH ILETIN II (PORK)
OCUCLEAR
OMEPRAZOLE MAGNESIUM
OPCON-A
ORUDIS KT
OXYMETAZOLINE HYDROCHLORIDE
PEDIATRIC ADVIL
PEPCID AC
PEPCID AC (GELTAB)
PEPCID COMPLETE
PERMETHRIN
PHARMASEAL SCRUB CARE
PIPERONYL BUTOXIDE; PYRETHRINS
POTASSIUM IODIDE
POVIDONE IODINE
POVIDONE-IODINE
PREVACARE R
PRILOSEC OTC
PRIMATENE MIST
PROFEN
PROSTEP
PSEUDOEPHEDRINE HCL
PSEUDOEPHEDRINE HYDROCHLORIDE
PSEUDOEPHEDRINE SULFATE
RANITIDINE
RANITIDINE HYDROCHLORIDE
REGULAR ILETIN II (PORK)
RID MOUSSE
ROGAINE (FOR MEN)
ROGAINE (FOR WOMEN)
ROGAINE EXTRA STRENGTH (FOR MEN)
SHADE UVAGUARD
SINE-AID IB
SODIUM CHLORIDE
SODIUM FLUORIDE; TRICLOSAN
SODIUM MONOFLUOROPHOSPHATE
STERI-STAT
SUDAFED 12 HOUR
TAB-PROFEN
TAGAMET HB
TAVIST ALLERGY/SINUS/HEADACHE
TAVIST-1
TERBINAFINE HYDROCHLORIDE
THEROXIDIL
THYRO-BLOCK
THYROSAFE
THYROSHIELD
TIOCONAZOLE
TRIVAGIZOLE 3
TYLENOL (CAPLET)
TYLENOL (GELTAB)
UNISOM
VAGISTAT-1
VASOCON-A
VELOSULIN BR
VISINE L.R.
VISINE-A
ZANTAC 150
ZANTAC 75
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